The Clinical Curative Effect Observation Of Treating Dyspepsia Induced By Chronic Cholecystitis Through The Combination Of Xiaoshilidan Capsules With Jiaolong Capsules

Objective:To observe the clinical curative effect of Xiaoshilidan capsule combined with Jiaolong capsule in the treatment of biliary dyspepsia induced by chronic cholecystitis.Methods:From September 2015 to January 2018,patients diagnosed as chronic cholecystitis with two or more dyspepsia symptoms in the hepatobiliary and pancreatic medical department were selected.A total of 132 patients with chronic non-calculous cholecystitis were divided into 4 groups randomly.Patients in the control group NO.1(n= 32)were given Danshu capsules(2 capsules,3 times a day).Patients in the control group NO.2(n= 32)were given Xiaoshilidan capsules(3 capsules,3 times a day).Patients in the control group NO.3(n= 32)were given Danshu capsules(2 capsules,3 times a day)combined with compound azinamide enteric-coated Tablets(2 tablets,3 times a day).In the experiment group NO.1(n= 35),patients were given Xiaoshilidan capsules(3 capsules,3 times a day)combined with Jiaolong capsules(2 capsules,3 times a day).There were 124 cases of chronic calculous cholecystitis,30 cases in the control group NO.4 were given Danshu capsules(2 capsules,3 times a day),32 cases in the control group NO.5 were given Xiaoshilidan capsules(3 capsules,3 times a day).There are 31 cases in the control group NO.6 in which patients take Danshu capsules(2 capsules,3 times a day)and compound azinamide enteric-coated Tablets(2 tablets,3 times a day).In the experiment group NO.2,31 cases were given Xiaoshilidan capsules(3 capsules,3 times a day)and Jiaolong capsules(2 capsules,3 times a day).All the above patients were treated for 4 weeks.The clinical symptom score was used to evaluate the changes of symptoms before and after treatment,and the treatment effect were analyzed.Results:1.The results of the chronic non-calculous cholecystitis patients after treatment.According to statistics,after the treatment the symptom scores were lower than before treatment,the experimental group NO.1 was better in alleviating symptoms such as the gallbladder area tenderness,upper abdominal pain,burning sensation in the upper abdomen,dry and bitter taste than that of the control groups,the difference was statistically significant(P < 0.05).The experimental group NO.1 and the control group NO.3 showed no statistical significance in alleviating the radiation pain in back and right shoulder,belching,early full and abdominal distension,loss of appetite(P>0.05).The experimental group NO.1 was better in alleviating the anaerobic greasy than the control group NO.1 and the control group NO.2,P<0.05.The improvement of abdominal symptom scores and the total effective rates of the experimental group NO.1 were significantly better than that of the control group NO.1 and control group NO.2(P<0.05),but showed no statistical significance compared with the control group NO.3(P>0.05).2.The results of the chronic calculous cholecystitis patients after treatment.It is shown that the experimental group NO.2 was better in alleviating symptoms such as radiation pain in back and right shoulder,gallbladder area tenderness,upper abdominal pain,burning sensation in the upper abdomen,dry and bitter taste than that of the control groups,the difference was statistically significant(P < 0.05).In relief of belching,early full and abdominal distension,loss of appetite,and anaerobic greasy there was no significant difference between the experimental group NO.2 and the control group NO.6(P>0.05),but there showed significant difference compared with the control group NO.4 and the control group NO.5(P < 0.05).The improvement of abdominal symptom scores and the total effective rates of the experimental group NO.2 were significantly better than that of the control group NO.4,control group NO.5 and the control group NO.6(P<0.05).Conclusion:1.The combination of Xiaoshilidan capsule with Jiaolong capsule can effectively relieve abdominal pain and various symptoms of dyspepsia induced by chronic cholecystitis,and the total effective rate after treatment is higher than using a single medication.2.The combination of Xiaoshilidan capsule with Jiaolong capsule is better in alleviating symptoms such as upper abdominal pain,gallbladder area tenderness,dry and bitter taste and burning sensation in the upper abdomen than the combination of Danshu capsule and Jiaolong capsule.However,there showed no difference in alleviating abdominal distension,belching,loss of appetite,etc.3.The therapeutic effect of Xiaoshilidan capsule combined with Xiaoshilidan capsule in treating chronic calculous cholecystitis patients was superior to the control groups.There showed significant difference in improving abdominal symptom scores and the total effective rates.