Correlation Of Pathological Type And Syndrome Of TCM Distribution Of Vulvar Dystrophy

Objective:This study aims to exploring the correlation of pathological type and syndrome of TCM distribution of vulvar dystrophy,so as to combines the pathological diagnosis and traditional Chinese treatment based on syndrome differentiation organically,in order to provide scientific basis for the clinical application of Chinese medicine for the treatment of this diseaseMethods: After a review of relevant literature and clinical observation,base on tutor experience and expert opinion to design questionnaires,set up seven type of syndrome,and collected in February 2015-December 2016 in line with menopausal hot flashes inclusion criteria for patients with a total 236 cases.Using EXCEL table to build information database,we can conclusions by using SPSS 21.0 statistical package for statistical data analysis: frequency analysis,cluster analysis,chi-square test.Results:(1)The study included 236 cases of patients with vulvar dystrophy,pathology reports showed that the sample included 161 cases of squamous hyp erplasia of vulvae,accounted for 68.22%,and 73 cases of lichen sclerosus of vul va,accounted for 30.93%,hybrid vulvar dystrophyin 2 cases,accounted for 0.85%;(2)In the syndrome classification,there are 92 cases of liver and kidney Yin deficiency syndrome,accounted for 38.98%;58 cases of dampness-heat of liver channel,accounted for 24.58%;44 cases of Yin deficiency with liver-yang hyperactivity,accounted for 18.64%;25 cases of spleen and kidney Yang deficiency syndrome,accounted for 10.59%,17 cases of blood deficiency wind dry permit,accounted for 7.20%;(3)In the quamous hyperplasia of vulvae,liver kidney yin deficiency syndrome in85 cases,liver 9 cases with damp heat syndrome,yin deficiency and hyperactivity of the liver in 35 cases,blood deficiency and wind dryness syndrome in 21 cases,11 cases of deficiency of spleen kidney;hardening,5 cases of liver kidney yin deficiency syndrome,liver yin deficiency and damp heat syndrome of hyperactivity of the liver in 49 cases.In 9 cases,4 cases of blood deficiency and wind dryness syndrome,6 cases of spleen kidney yang deficiency syndrome,2 cases were mixed type,liver kidney yin deficiency syndrome.The proportion of TCM Syndromes of squamous epithelial hyperplasia and lichen planus type vulvar dystrophy was statistically significant(P<0.01).(4)Vulvar dystrophy patients with liver kidney yin deficiency syndrome in patients with squamous cell hyperplasia in 85 cases,5 cases of lichen sclerosus type,2 cases of mixed type;9 cases with hepatic squamous epithelial hyperplasia type of damp heat syndrome in patients with lichen sclerosus type 49 cases;35 cases of yinxuganwang squamous epithelial hyperplasia syndrome in patients with atherosclerosis a total of 9 cases of lichen;squamous epithelial hyperplasia type of blood deficiency and wind dryness syndrome in 21 cases,a total of 4 cases of lichen sclerosus type;squamous epithelial hyperplasia of spleen kidney yang deficiency syndrome in 11 cases,a total of 6 cases of lichen sclerosus type.Through the statistical analysis of liver kidney yin deficiency syndrome,liver pathological type distribution of damp heat syndrome and other syndromes than there were statistically significant differences(P<0.01),no significant pathological type distribution of ganshenyinxu,blood deficiency and wind dryness and deficiency of spleen and kidney yang and other syndromes difference(P>0.05).(5)Of the 236 patients with vulvar dystrophy,139 were postmenopausal and 97 were premenopausal.There were 90 cases of squamous hyperplasia,2 cases of menopause,71 cases of non menopause,47 cases of postmenopausal patients in lichen sclerosis,26 cases of non menopausal patients,and mixed malnutrition,all of them were menopause.The menopause of liver kidney yin deficiency syndrome in 52 cases;40cases of premenopausal;liver damp heat syndrome in postmenopausal women in 38 cases,20 cases of premenopausal;yinxuganwang menopause syndrome in 23 cases,21 cases of premenopausal;postmenopausal patients with blood deficiency and wind dryness syndrome in 14 cases,11 cases were premenopausal;12 cases of postmenopausal patients with spleen kidney yang deficiency,5 cases without menopause;menopausal status and pathological type of each TCM syndrome constituent ratio of the difference was not statistically significant(P>0.05).(6)In 236 cases of vulvar dystrophy,the course of disease is less than 1 years,a total of 75 cases,1-3 years of 67 cases,3-5 years of 53 cases,5-10 years of 25 cases,more than 10 years of 16 cases.The course of disease was less than 1 years.Squamous epithelial hyperplasia was found in 51 cases and lichen sclerosis type in 24 cases.The course of the disease was 1-3 years.Squamous epithelial hyperplasia was found in 45 cases,lichen sclerosis type in 18 cases and mixed type in 1 cases.The course of the disease was 3-5 years.Squamous epithelial hyperplasia was found in 38 cases,lichen sclerosis type in 17 cases,mixed type in 1 cases.In 5-10 patients,squamous epithelial hyperplasia occurred in 17 cases and lichen sclerosis type in 9 cases.The course of disease is more than 10 years,squamous intraepithelial hyperplasia in 10 cases,lichen sclerosis type in 5 cases.There were 28 cases of liver and kidney insinuation,19 cases of hepatocliosis,13 cases of the liver,and 8 cases of dysplasia,and7 cases of spleen and kidney.There were 25 cases of liver and kidney insinuation of liver and kidney in patients in 1 to 3 years of illness,17 cases of hepatocyanic syndrome,12 cases of Yin deficiency liver,7 cases of dysplasia,6 cases of spleen and kidney,and 6cases of spleen and kidney.There were 22 cases of liver and kidney insinuation of liver and kidney in patients in 3 to 5 years,13 cases of hepatocolecular fever,10 cases of Yin and foie liver,5 cases of dysplasia,3 cases of spleen and kidney,and 3 cases of spleen and kidney.There were 11 cases of liver and kidney insinuation of liver and kidney in patients in 5-10 years,6 cases of hepatic heat and humidity,5 cases of Yin deficiency liver,and 3 cases of dysplasia,and 0 cases of spleen and kidney.Course of more than 10 years,6 cases of liver and kidney Yin deficiency syndrome in patients with liver after damp heat syndrome(3 cases),Yin deficiency of liver syndrome in 4 cases,blood deficiency wind dryness syndrome in 2 cases,spleen and kidney Yang deficiency syndrome in 1 case,various pathological types and clinical course of TCM syndrome types of composition than difference has no statistical significance(P > 0.05).Conclusion:(1)In this study type squamous epithelial hyperplasia vulvar dystrophyrate significantly more than the sclerosing moss type vulvae malnutrition,mixed vulvar dystrophy accounted for the least proportion;(2)This study the TCM syndrome types of vulvar dystrophy,the rate of sufferer of in liver and kidney Yin deficiency syndrome are the most,and the second are dampness-heat of liver channel,followed by Yin deficiency with liver-yang hyperactivity,blood deficiency wind dry,spleen and kidney Yang deficiency permit;(3)Squamous epithelial hyperplasia in vulvar dystrophyin patients with liver and kidney Yin deficiency syndrome is the most rare,lichen sclerosus of vulva in dampness-heat of liver channel syndromeis the most rare;(4)In patients with liver and kidney Yin deficiency syndrome the one with Squamous epithelial hyperplasia took tne highest incidence,in the liver meridian dampness heat syndrome the patients with lichen sclerosus of vulva took tne highest incidence.(5)The pathological type of vulvar dystrophy is associated with the syndrome of TCM distribution;(6)Pathological type and TCM syndrome types of vulvar dystrophy are has nothing to do with the state of menopause;(7)The pathological types and TCM syndrome types of vulvar dystrophy were unrelated to the course of disease.