| Objective: To count the number of benign and malignant eyelid tumor in our hospital in the past 10 years,and to explore the correlation between the property of tumor and age,sex,eye,location,course,size,and to analyze the surgical technique of different skin defect.Methods: To analyze the clinical data of 238 patients with eyelid tumor who were admitted to our department and met the inclusion criteria in January 2008 to February2019.The data includes the property of tumor,age,sex,eye,locations,courses,sizes,surgical methods and recoveries after surgery.Results:(1)Among the 238 cases,there were 102 males(accounting for 42.86%)and 136 females(accounting for 57.14%);The age ranged from 1 to 89 year s,the average age was 59.55±16.37.(2)Among 238 cases,there were 120 cases in right eye(accounting for 50.42%)and 118 cases in left eye(accounting for 49.58%),there were 95 cases in upper eyelid(accounting for 39.92%),120 cases in lower eyelid(accounting for 50.42%),16 cases in inner canthus(accounting for 6.72%),and 5 cases in outer canthus(2.10%).(3)The course of disease ranged from15 days to 40 years.The size was 2*1*1mm3 to 20*12*3mm3.(4)Among 238 cases,there were 99 cases of malignant tumors,accounting for 41.60%,basal cel l carcinoma(71 cases,accounting for 71.72%)had the highest proportion of malig nant tumors,the second was squamous cell carcinoma(13 cases,accounting for 13.13%).Follow squamous cell carcinoma,there were 8 cases of meibomian gland c arcinoma,accounting for 8.08%,2 cases of malignant melanoma,accounting for2.02%,2 cases of sebaceous carcinoma,accounting for 2.02%,1 case of cutaneo us mucinous carcinoma,1 case of small round cell malignant tumor and 1 case of poorly differentiated carcinoma,each accounting for 1.01%.(5)Among 238 cases,there were 139 cases of benign tumors,accounting for 41.58.40%,benign epit helial tumors(60 cases,accounting for 43.17%)had the highest proportion(they inc luded 41 cases of seborrheic keratosis,accounting for 29.50%,14 cases of squa mous papilloma,accounting for 10.07%,4 cases of keratoacanthomas,accounting for 2.88% and 1 case of fibroepithelial polyp,accounting for 0.72%).Secondly,t here were 37 cases of benign melanoma(accounting for 26.62%)(included 29 c ases of intradermal nevus,accounting for 20.86%,6 cases of compound nevus,a ccounting for 4.32%,2 cases of junctional nevus,accounting for 1.44%);there were 17 inflammatory lesions,accounting for 12.23%,10 cysts,accounting for 7.19%,3 calcifying epitheliomas,accounting for 2.16%,3 angiomas,accounting fo r 2.16%;2 mixed tumor,accounting for 1.44%,hidroadenoma,subcutaneous sch wannoma,hyperplasia of sebaceous glands,solitary fibrous tumor,xanthoblastoma,ductal dilation of lacrimal gland and trichoblastoma were found in 1 case each,accounting for 0.72%.(6)The number of benign and malignant eyelid tumor sho wed an increasing trend with the increase of age.(7)The number of eyelid tumo r increased progressively year by year.(8)There were significant differences betw een benign and malignant eyelid tumor on the age of onset(P < 0.05);But they had no difference on the sex,eye and location.(9)The malignant degree of eyeli d tumor was positively correlated with age(P < 0.05,?=2.172).(10)The age of b enign and malignant eyelid tumor conformed to normal distribution.The age of high incidence of malignant tumors was 65.89±11.96 years,and the age of high incidence of benign tumors was 55.05±17.58 years.(11)In my study group,there were 102 cases of vertical sliding flap,and only one patient had slight lower e yelid ectropion whose eyelid tumor closed to lower lacrimal puncta,and the eyel id morphology and function of the other patients recovered satisfactorily.(12)Exc ept for three of all malignant tumors undergoed evisceration of orbit contents,Fo r other patients,the range of peripheral skin resection was 5~8mm after the froz en section showed that the resection margin was negative.(13)Basal cell carcino ma was more common in lower eyelid(43 cases,accounting for 60.56%),followed by upper eyelid(17 cases,accounting for 23.94%),inner canthus(9 cases,ac counting for 12.68%),and outer canthus(1 case,accounting for 1.41%).Conclusion:1.Basal cell carcinoma had the highest proportion of malignant tumors,the second was squamous cell carcinoma.2.Benign eyelid tumor which is difficult to distinguish from malignant eyelid tumors included benign epithelial tumors(seborrheic keratosis is the most common),benign melanin neoplasms(intradermal nevus)and inflammatory lesions.3.The malignant degree of eyelid tumor was positively correlated with age(P < 0.05,?=2.172).4.There were significant differences between benign and malignant eyelid tumor on the age of onset(P < 0.05);But they had no difference on the sex,eye and location.5.The age of high incidence of malignant tumors was65.89±11.96 years,and the age of high incidence of benign tumors was 55.05±17.58 years.6.When the transverse diameter of the skin defect is greater than 1/3 of the total length of the eyelid margin,less than or equal to 1/2,and the longitudinal diameter of the defect is within the compensation range of the eyelid skin relaxation,the vertical sliding flap is a safe and effective repair method.When the skin defect closes to lower lacrimal puncta,the choice of the vertical sliding flap should be cautious.7.For malignant tumors without obvious signs of infiltrating growth,the resection of the 5 ~8mm normal skin around the root of the tumor can often achieve a satisfactory resection effect. |
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