Effects Of 8-week Altitude Training On Rowers Erythropoiesis And Iron Metabolism

Background: Altitude training has complex physiological and biochemical training effects on rowers.The adaptation of athletes from initial altitude to hypoxia and hypoxia is a process in which circulatory and respiratory system functions gradually change,especially blood composition and biochemical effects.When training at altitude,athletes should monitor the process of exercise and hypoxia stimulation to form a more systematic and perfect monitoring index system of altitude training in rowing events.In the final stage of preparation for the national games,the shanghai rowers will train on the plateau for eight weeks.This study attempted to analyze the effects of eight weeks of altitude training on erythropoiesis and iron metabolism in rowers.Objective: To explore the effect of 8 weeks of altitude training on hematologic indexes of rowers,and to compare and analyze the physiological and biochemical indexes of rowers before and after altitude training to explore the effect of altitude training on erythropoiesis and iron metabolism of rowers,and to provide more theoretical basis for physiological and biochemical monitoring of rowers.Results:(1)after 8 weeks training,RBC,HGB,HCT,MCV and MCH in AT group increased significantly(P<0.05),MCHC and RDW-CV decreased significantly(P< 0.05),RDW and RDW-SD did not change,RBC,Hgb,HCT,MCV,MCH,MCHC,RDWSD,RDW-CV and RDW were not changed in St Group.There was significant difference between AT group and St Group after 8 weeks training(+4.95% vs-3.21%,p=0.003,η2= 0.298;+6.48% vs-1.57%,P=0.002,η2=0.317).RBC,MCHC,RDW,RDW-cv and RDWSD of AT group and St Group had no significant changes.(2)after 8 weeks training,LFR in AT group increased significantly(P<0.05),MFR and IRF decreased significantly(P<0.01),RET-He,RET and HFR did not change significantly,RET-He in St Group decreased significantly(P<0.05),there were no changes in RET,LFR,MFR,HFR and IRF.(3)IRON METABOLISM: After 8 weeks of altitude training,Fer in AT group decreased significantly(P<0.01),s Tf R,s Tf R/log SF,HEP increased significantly(P<0.05),and EFRE did not change.ERFE and Hep were significantly increased in St Group(P=0.013;P<0.05),but Fer,s Tf R and s Tf R/LOGSF were not changed.The changes of Fer,EFRE,s Tf R,s Tf R/log SF and Hep were significantly different between AT group and St Group(-36.16% vs-2.96%,P=0.040,η2=0.152;+17.99% vs + 121.31%,P=0.013,η2=0.215;+82.77% vs-8.87%,P=0.025,η2=0.119;+146.77% vs + 86.86%,P=0.029,η2=0.177).Conclusion:(1)High altitude training increases the number of red blood cells,improves the activity of red blood cell production in the body,and has a positive effect on the ability of athletes to carry oxygen.(2)After 8 weeks of altitude training,the growth activity of bone marrow erythrocytes decreased and the growth rate of reticulocytes decreased.High altitude hypoxia stimulation and exercise training can accelerate the growth of immature red blood cells.(3)Higher iron demand induced by altitude training leads to increased use of iron reserves,increased expression of s Tf R,increased iron uptake in red blood cells mediated by it,and enhanced iron transport,thus promoting the synthesis anddifferentiation of hemoglobin and erythrocytes.This is when ferromodulin begins to maintain the iron balance,inhibits iron output and replenishes iron reserves by promoting the internalization of membrane iron transporter proteins by increasing ferromodulin expression.