Objective:To explore the effective therapeutic method of combination of TCM and western medicine to postpone renal function deterioration of diabetic nephropathy.Method:According to WHO diagnosis criteria and TCM differentiation criteria, we selected 60 cases (29 male and 31 female), Which were divided into two groups (A and B) at random.Two groups have no significant difference by statistics in age,sex,urine protein/24h and serum creatinine.With control die,sport and have hypoglycemic drug or subcutaneous injection insulin therapy to control blood glucose strictly , fasting plasms glucose(FPG) < 7.0mmol/L,glycosylated hemoglobin <8%,A group was treated by Lotensin ( 10mg-20mg. Qd ) for 2 months,B groups was treated by both yiqihuoxue decoction and Lotensin for 2 months,detected urine protein /24h, serum creatinine(SCR) and blood uria nitrogen(BUN),observing marker indicated by mean and standard deviation before and after theraphy,contrasted by pairedsample T-Test or independent sample T-Test between before and after theraphy for two groups.Result: Scr and BUN of A group had no significant difference than those of B group (p>0.05 ) . urine protein/24h of two groups descented after theraphy , which has signficance difference in statistics . B group is prior to A group.Conclusion: It's better to treat with combination of TCM and western medicine than only ACEI in postponing renal function deterioration of diabeticnephropathy and progressing life quantity.
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