Clinical and experimental studies have demonstrated that osseointegration could be achieved under the immediately implanted and immediately loaded conditions. These two conditions all can independently improve bone formation around implants, whether these two potentials can be simultaneously utilized during the initial implanting process. Evaluation of progressive vertical loaded implants placed in fresh extraction sockets on tissue ultrastructure in vivo will therefore aid in the understanding of the mechanisms of the bone-implant interface. The aim of this study was to compare differences in early bone-biomaterials interaction and reactions between the progressive vertical loadings and the non-loadings of implants placed into extraction sockets.Six beagle dogs, male, 18-month old, and with a mean body weight of 15±0.5kg were used in this study. In order to fix the X-ray films and control the angel of the X-ray project in, the film frame were made according to their mandibular model before operation. Under anesthesia, each dog was...
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