Relative Factors Analysis On Laryngeal Cacinoma Recurrence Including Carcinoma Marker,Molecular Margin And Clinical Factors

Objective:Laryngeal carcinoma is one of the most common malignant neoplasms in the otorhinolarynogology head and neck surgery. Laryngeal carcinoma recurrence is common after operation.The factors of laryngeal carcinoma recurrence is comprehensive.To explore the factors of laryngeal carcinoma recurrence,in this article ,103 patients of laryngeal carcinoma were analyzed retrospectively on carcinoma marker ,molecular margin and clinical factors with univariate analysis and multivariate analysis.Methords:CyclinD1 , P27, P53 and eIF4E in primary site were detected in laryngeal carcinoma recurrence group and unrecurrence group with immunohistochemical staining to explore the significance of CyclinD1 , P27, P53 and eIF4E in primary site on laryngeal carcinoma recurrence; CyclinD1, P27, P53 and eIF4E in surgery margins were detected in laryngeal carcinoma recurrence group and unrecurrence group with immunohistochemical staining to explore the significance of CyclinD1, P27, P53 and eIF4E in surgery margins on laryngeal carcinoma recurrence. The clinical data of 103 patients of laryngeal carcinoma were analyzed retrospectively to explore the clinical factors of laryngeal carcinoma recurrence; At last above three factors were analyzed with multivariate analysis.Result:There was significant difference between laryngeal carcinoma recurrence group...