Clinical And Empirical Study Of Mechanism In Protection Acute Cerebral Infarction By Scalp-Point Penetrative Acupancture

Objective:penetration through the scalp acupuncture group and thegeneral,drug control group,the treatment of acute cerebral infarctionneurological deficit scores of the comparative study,from the nervous andimmune aspects of chemical and biological protection mechanism of thebrain to the first hole to guide through gill treatment of acute cerebralinfarction.Methods:All patients randomly assigned to adopt the methods,divided into three groups:the first penetration hole group of 40 patients (thefirst hole through barbed + drug),40 cases of ordinary acupuncture group(general acupuncture + drug),40 cases of the control group (simple druggroup).1.Clinical Research:14 days after treatment,the neurological deficit scoresmeasured.2.Experimental Study:(1) All patients were treated before the 7th day after treatment,the first 14days of fasting blood collection,ELISA enzyme-linked immunosorbent assayfor detection of SOD,MDA,TNF-α,IL-6,NO,ET(2) All patients were treated before the 7th day after treatment,the first 14days of fasting blood for automaticamino acid analyzer GLU,ASP(3) in the treatment of all patients before the 7th day after treatment,thefirst 14 days of fasting blood collection,the use of automatic biochemicalanalyzer for determination of serum Mg2 +,Ca2 +Results:1.14 days after treatment,scalp penetration acupuncturegroup of patients the degree of neurological deficit and improving theassessment of clinical efficacy was significantly better than the two controlgroups (P＜0.05 and P＜0.01),describes the scalp penetration acupuncture onacute cerebral infarction sure clinical efficacy. 2.14 days after treatment,serum Mg2 + levels decreased significantly,Ca2+ content was significantly increased.Penetration point and the first groupand the control group (P＜0.0 1);IL-6,TDNF-αdecreased in the first holegroup penetration compared with the control group had significant difference(P＜0.01);NO,ET content decreased scalp penetration acupuncture groupcompared with the control group had significant difference (P＜0.01);GLU,ASP decreased the content of the first hole group penetration compared withthe control group had significant difference (P＜0.01) SOD significantlyincreased the content,MDA content was lower scalp penetration acupuncturegroup compared with the two control groups were significantly different (P＜0.01).Note scalp penetration acupuncture help to reduce brain tissuedamage in acute cerebral infarction,which play a role in brain protection.Conclusion:Hole through a barbed significantly in patients with acutecerebral infarction to improve the neurological deficit score,more effectivethan ordinary acupuncture group and the drug control group.Point 2 can be integrated through barbed adjusted free radicals after acutecerebral infarction,endothelin and nitric oxide,excitatory amino acids,calcium overload,inflammatory cytokines,which play a comprehensive andsystematicrole in cerebral protection.