Research On Rule Of Exercise-induced Lower Hemoglobin And Its Haematogenous Mechanism

It was reported that in recent years the number of athletes suffered with sports anemia has been less than it was before. Nevertheless, the reduction of hemoglobin concentration, caused by training, but not reaching the criteria of sports anemia has been often seen. This phenomenon induces the decrease of erythrocyte in O2 and CO2 transport as well as energy metabolism, the result of which is the decrease of exercise capacity. As for the new problem of exercise-induced lower hemoglobin, it was failed to find any report of its effects on haematogenous mechanism and methods for forecasting it. Therefore, the purpose of this study is to explore the haematogenous mechanism of exercise-induced lower hemoglobin and the diagnosis of its early changes by means of animal and human experiments. In animal experiments, when exercise-induced lower hemoglobin occurred in the rats having their incremental loading swimming training for 8 weeks its effects on hematopoietic factors, iron metabolism and erythropoiesis were studied systematically. In human experiments, the changes of haemocyte parameters were studied longitudinally for more than one year in elite swimmers having their normal training. The main results are as follows:1. A new type of swimming apparatus with flowing water for rats has been developed. A model of rats with exercise-induced lower hemoglobin, having their incremental loading swimming training in flowing water for 8 weeks has been established.2. In the exercise group, when the rats'hemoglobin concentration decreased, the amount of their reticulocytes increased significantly. Among them, the percentage of the immature reticulocytes increased, but the fraction of the mature reticulocytes decreased. The volume of the reticulocytes increased, but the distribution width of the mean cell hemoglobin concentration decreased. The hemoglobin contents of the reticulocytes increased, and the reticulocyte cell hemoglobin distribution width also increased. In the course of the decrease of hemoglobin, induced by exercise, the reticulocyte count and their subtype parameters changed one week earlier than hemoglobin and erythrocytes did.