Urinary Stone Analysis With Fourier Transform Infrared Spectroscopy (520Cases)

Urinary stone analysis is important technology in determining thepossible etiology and the pathophysiology of stone formation. A betterunderstanding of the stone composition may be helpful in preventing urinarystone formation. From September2009to December2011,520urolithiasispatients from Urology Department in Wuhan Tongji Hospital after surgerytreatment or atfer shock wave lithotripsy, or atfer stones spontaneous passagewere taken part in the study. Stone compositional analysis was performedusing fourier transform infrared spectroscopy. The results showed that themost frequent composition in173pure stone (33.3%) was calcium oxalate(19.8%), followed by calcium phosphate (9.2%), xantine (2.5%), L-cystine(1%), silica (0.4%), uric acid (0.2%) and quartz (0.2%).347(66.7%) weremixed stone, calcium oxalate was the most commonly major component(34%), followed by calcium phosphate (22.7%), uric acid and cystine. In ourcase，the most commonly found pure stone was calcium oxalate，while themost frequent mixed stone was calcium oxalate and calcium phosphatemixture. The relationship between stone location, gender, age and stonecomponents were showed. We present some results of analysis of urinary tractstones extracted from patients using FTIR spectroscopy and show specificfeatures of urinary tract stone composition and may help improveunderstanding of the urolithiasis pathophysiology.