The Study On Preparation And Primary Quality Standard Of Yanlixiao Intestinal Pellets

Recently, with the development of new TCM preparations and new technology, the application of pellets has been paid more and more attention and become a promising TCM preparations. It not only took the independent dosage-form also has the very manypreparations variety. Compared with traditional dosage forms,its external form is beautiful, the fluidity is good; have medicine inside amounts are big , take dosages small; releases the medicine stably, reliable; the relative surface accumulates in a big way, dissolves quickly; Living things makes use of degree height.YANLIXIAO intestinal pellets is a type of modern TCM preparations extracted from Folium syringae and made scientific method, It has marked antiseptic and antiviral curative effects. It has antiseptic and antiviral curative effects. So, coating YANLIXIAO pellets can achieve the goal of treating the intestines DEP artment diseases.This study prepared pellet cores with extrusion-molded method, after the prescription factor and the craft factor inspected, we determined YANLIXIAO intestinal pellets the preparation craft.The method of revolving pot coating contains pill core by intestinal materials. The single factor inspection has established the coating craft. Acrylic acid resin II, III was the main thin film coating material, the coating pellet rate of finished products was high, finished produce can achieve at the intestines DEP artment release request by dissolve determination in vitro. At the same time the syringpicroside was qualitative Investigation by the thin layer chromatography and quantitative investigation by HPLC Thus the quality standard of YANLIXIAO intestinal pellets was set up.This research has provided the scientific basis for the big production, laid the foundation for the raw material for medicine and the preparation standardization, and has provided the feasible reference for the traditional Chinese medicine modernization advancement.