The Study Of Distributed Regularity Of Traditional Chinese Medical Syndrome In Chronic Gastritis

Background and Purposes:The Chronic Gastritis is that different reasons cause the chronic inflammation or atrophic change of gastritis mucous membrane, which is a familiar clinical disease. It has high inciden -ce rate, above 90% those patiens who accept the stomach endoscopical examining , and the incidence rate go up with the trend of age growth. Currently the outbreak mechanism of the CG is mainly Helicobacter pylori (HP), food and environment factor etc., which cause the slow inflam -mation of stomach mucous membrane, therefore, there are many therapy means, such as eradicating HP, antacids or repressing acid .promoting stomach and intestines power ect. But a lot of clinical patients can ease or alleviate the symptom when they take the medicine , and cause to relapse again behind stoping it . CG can belongs to the categories of "stomach -ache" and "distention and fullness" etc. .which have no responseed disease in TCM. And it be thought that it have mainly relation with food, feeling factor, esogenous evils, the poor transportation and transfor -mation of spleen and stomach... etc. The directed affected position lies in large stomach ,but the onset of CG is closely related with liver and spleen, the key of the disease pathogenesis mainly is the poor transpo -rtation and transformation of spleen and stomach. TCM has the theory to treat the patient according to the syndromes and is good at treating such relapsed easily disease.Currently typing according to syndrome differentiation of CG is not unified. Though there has been the standard which mainly come from the discussion and collective researches of parts of home expertses, and is short of the clinical Epidemiology of TCM pathogenisis .baffling its canonical treating according to the syndromes at certain degree, further affecting the exaltation of the clinical whole curative effect of TCM.This research adopt the way of combineing the epidemiological study and the strict modern statistics method, which tries to find the mainsyndrome of CG , the distribution of them and the relativity between them and the part correlative result of checking.Participants:296 consistent cases who see doctors to the GuangDong Provincial Hospital of TCM and be diagnosed with CG during May 2004 to March 2005.Methods:Firstly, we designed the Investigation Format of TCM on the basis of the anylasis result of the related articles and books. Secondly, we just investigated CG patients and make records carefully. Thirdly we Inpute and check the investigated data adopting the SPSS 10.0, and estab -lish a syndrome differentiation measureing form, whose sensitivity and specificity are validated by experts, of basic syndromes of TCM on non -atrophic chronic gastritis for computer using on the foundation of reading many articles, combineing three presently relatively authori -tative syndrome differentiation reference standards of TCM pathogenesis on CG. Then getting the basic syndrome of every case through differentiat -ion of syndrome adopting the calculator. Lately the statistics method involved are the descriptive method , the Hiearchical Cluster method , multidimensional scaling analysis and correlating analysis.Results:About the basic CG syndrome are deficiency of the pleen and stomach syndrome (160 cases , covered 54.1%), hepatic qi affects the stomach syndrome(151 cases, covered 51. 0%), the depressed liver with the insuffici -ent spleen syndrome(113 cases .covered 37.2%)and deficiency of the spleen and stagnation of qi syndrome(110 cases , coveres 37. 2%)according to frequencies analysis. Synthetizing hierarchical clustering and multidi -mensional scaling analysis, deficiency of the pleen and stomach is the basic pathogenesis of CG,there are four most familiar basic syndromes including deficiency of the pleen and stomach syndromes, hepatic qi affects the stomach syndrome, the depressed liver with the insufficient spleen syndrome, deficiency of the spleen and stagnation of qi syndrom -e. They all are familiar syndromes of CG together with heat and dampness in the spleen and stomach syndrome, deficiency of stomach-yin syndrome, and statis and heat of liver and stomach syndrome.Correlate analysis prompts that the eroded stomach mucosity is ofen seen in heat and dampness in the spleen and stomach syndromes, deficiency of stomach-yin syndromes and statis and heat of liver and stomach syndrome; bile being seen in hepaticqi affects the stomach syndrome.According to results of the Hiearchical Cluster method, we find that four primary clinic syndromes are hepatic qi affects the stomach., deficie -ncy of the spleen and stagnation of qi syndrome (including the depressed liver with the insufficient spleen syndrome), deficiency of the pleen and stomach syndrome, heat and dampness in the spleen and stomach,statis and heat of liver and stomach syndrome, deficiency of stomach-yin syndrome.The common symptoms of hepatic qi affects the stomach, deficiency of the spleen and stagnation of qi syndrome(including the depressed liver with the insufficient spleen syndrome)are as follows: epigastric distensi -on and pain or involved pain in hypochondrium, eructation, regurgitation of acid, stingy pulse, pale tongue with whitish coating;gastralgia or distention of the epigastriom, which outbreak after eating foods, nada -i, often tired, the stool is altered from loose to dry, week pulse, enlarged or indented tongue, loose stool or feeling of incomplete and difficult evacuation, stringy pulse.The main manifestation of deficiency of the pleen and stomach syndrome are as follows:gastralgia, outbreak when feeling hunger, often tired, en -joying pressed, impaired appetite, diarrea, pale tongue with whitish coating, enlarged or indented tongue, deep or thin pulse.The sign in the heat and dampness in the spleen and stomach, statis and heat of liver and stomach syndrome are as follows:epigastric, eruc -tation, regurgitation of acid, dry mouth and bitter taste, feeling of incomplete and difficult when stool evacuated, yellowish urine, redness of the tongue, yellowish glossy coating of the tongue, smooth or stringy pulse.The main symptoms of deficiency of stomach-yin syndrome are as fol lows: gastralgia, eructation, dry mouth, the stool is hard and dry, inso -mnia, redness of the tongue,stringy or thin pulse.Conclusions:The basic pathogenesis of CG is the pleen and stomach. The basic CG syndrome are deficiency of the pleen and stomach syndrome, hepatic qi affects the stomach syndrome, the depressed liver with the insufficient spleen syndrome and deficiency of the spleen and stagnation of qi syndrome. They all are familiar syndromes of CG together with heat and dampness in the spleen and stomach syndrome, deficiency of stomach-yin...