Research On The Correlativity Between TCM Syndrome Ofmetabolic Syndrome And IR,LEP

Objectives: to study the relationship between the Chinese medicine syndromes of MS and IR,LEP, and exploring the difference of syndrome and type in such patients, which provide the dialectical way and the theoretical basis of combined medicine treatment.Methods: we selected 80cases, and divided them into four Chinese medicine syndrome groups which include liver-fire exuberant syndrome, phlegm-dampness abundant syndrome, phlegm and blood stasis syndrome, Qi and Yin deficiency syndrome, deficiency of Yin and Yang syndrome, 20 healthy people were taken as a normal control group. we take their blood pressure,height,weight and waistline. We detected fasting plasma glucose (FPG), triglyceride (TG), high density lipoprotein-cholesterol (HDL-C), fasting Insulin (FINs), Leptin (LEP) through taking suction from Venous blood. The insulin sensitivity index (ISI) values: ISI=-ln/ (FPG×FINs). Early the next morning began collecting urine specimens. Collecting complete 24h urine samples submitted after the detection of urinary albumin concentration (imunoturbidimetry).Results: The LEP in MS group is higher than the control group (p <0.05), positive correlation was found between serum leptin and insulin sensitive index,and there was also a positive correlation between LEP and BMI,SBP,FPG,ISI,FINS,and TG. (p <0.05), the heightening level of LEP was deficiency of Yin and Yang>Qi and Yin deficiency syndrome > phlegm and blood stasis syndrome > phlegm-dampness abundant syndrome>liver-fire exuberant syndrome, the ISI of MS group was significantly lower (p <0.05),the degree of ISI lowing level was liver-fire exuberant syndrome