Effect Of Jin Fu An Decoction In Improving Quality Of Life And Mentation Of Patients With Medium Or Late Stage Non-small Cell Lung Cancer

ObjectiveTo observe the effect of Jin Fu An Decoction in improving quality of life of patients with non-small cell lung cancer(NSCLC) inⅢorⅣstage.Methods60 patients with medium or late stage non-small cell lung cancer were divided randomly into three groups.In Jin Fu An Decoction Group,20 patients were treated with Jin Fu An Decoction alone.In The Best Supportive Care Group, 20 patients were treated with medicine just relieve ailment alone.In Targeted Therapy Group,20 patients were treated with SSTR-targeted.Six items, including physical status,social/family status,intercourse with physicians, emotional status,functional status and additional concerning status,were investigated and analyzed by using Functional Assessment of Cancer Therapy-lung(FACT-L).Major depression and Anxiety disorder were investigated and analyzed by Self-Rating Deprssion Scale and Self-Rating Anxiety Scale.Each patient was measured quality of life 2 times,before the treatment when the patient had hospitalized within 24 hours,and the 21th day of treatment.ResultsIn the physical status,emotional status,functional status and additional concerning status,the scores among the three groups was that Jin Fu An Decoction Group and Targeted Therapy Group was superior to The Best Supportive Care Group(P＜0.05),however,Jin Fu An Decoction Group and Targeted Therapy Group compared with no significant difference(P＞0.05).In the intercourse with physicians,all thegoups good effect and the three Groups compared with no significant difference(P＞0.05).In the social/family status,none the three groups have significant effect.In the depression and anxiety status, the scores among the three groups was that Jin Fu An Decoction Group and Targeted Therapy Group was superior to The Best Supportive Care Group (P＜0.05),however,Jin Fu An Decoction Group and Targeted Therapy Group compared with no significant difference(P＞0.05).ConclusionThe Jin Fu An Decoction can elevate the quality of life and the mental state of the patients with medium or late stage non-small cell lung cancer. however,Jin Fu An Decoction Group and Targeted Therapy Group compared with no significant difference.