Study On The Effects Of Fructose-1, 6-diphosphate On Enzyme Activity And Free Radical Metabolism Of Both Skeletal Muscle And Blood In Exercise-induced Fatigue Rats

The author observes effects of fructose-1, 6-bisphosphate on CK, LDH, SOD and MDA of both skeletal muscle and blood on exhausted rats by increasing workloads training and its variation. This study inquires into FDP's protected function of the skeletal muscle and the dynamic variation that FDP delays the exercise-induced fatigue and facilitates the removal of fatigue in the course of recovery. Ninety male Sprague-Dawley rats were randomly divided into 9 groups(n=10), they are untrained group (UT, 1 group), trained control group(TC, 4 groups) and medicine- treated trained group(TT, 4 groups).TC and TT groups were endurance trained 5 days weekly for 7 weeks on a motorized treadmill and exhausted in the last training. TT groups received intraperitioneal (i.p.) injection with 1g/kg of body mass of FDP immediately after training each time. FDP was injected 50 minutes before the last training. TC groups were i. p. injected with saline of the same volume accordingly. Five weeks later, immediate after exhaustion by training 7 weeks, 6 hours and 24 hours after exhaustion by training 7 weeks, superoxide dismutase(SOD), Lactate dehydrogenase(LDH), creatine kinase (CK) and malondialdehyde(MDA) were measured in the skeletal muscle and plasma respectively. Same parameters...