Sore Plaster Quality Standards And Preliminary Stability Study

"ChuangJie Plaster" is made on basis of the experimental prescription, which is made of several Chinese herbs, including Ephedra sinica Stapf, Radix et Rhizoma Rhei,Panax notoginseng, etc. It can cure the surgery hurts, operation wounds and the wounds on the surface. "ChuangJie Plaster" has the characters of quick effects and easy to use. Now we were researching this drug according to the national new-drugs, including quality standard and stability test. Therefore, it provides the scientific proof for its clinic effect.In aspects of the quality standard and stability test: we investigated the use of TLC on the separation and identification for Ephedra sinica Stapf, Radix et Rhizoma Rhei,Panax notoginseng in the "ChuangJie Plaster". The content of Ephedrine Hydrochloride in the "ChuangJie Plaster" was determined by HPLC. The results showed that the method was simple, special and accurate, it could exact as a reliable base for quality control of this preparation. In order to inspect stability of "ChuangJie Plaster", the room temperature and the accelerate test for three months had been carried out. The results showed that every index mark were normal in the experiment period.The research work was under the direction of the theories of Chinese traditional medicine external therapy, and united with modern preparation technology to exploit a kind of lower dosage, good application, lower cutaneous anaphylasis and converient new dosage form, which could lay thefoundations of creating more social benefit and economical benefit.