| Objective: Through filling the compound of Chinese traditional sturdy-positive-medicine prescriptions to the big mouse , observe the medicine and training's influence through determining free radical metabolism of cardiac muscle, PLA2 and GOT's active, clarify its mechanism of anti-fatigue and mobility increase, provides the scientific basis for better instruction movement training and the enhancement movement ability, and lay the foundation of the Chinese traditional medicine development which suits the athlete drinks for the next step.Method: 128 male wister big mouse were randomly selected and divided into group A (peaceful group), group B (movement group), group C (peacefully fortifies yang group) and group D (movement fortifies yang group). After B and D group were trained for 8 weeks, Group C and D were filled with the compound of Chinese traditional sturdy-positive-medicine prescriptions every day. Eight weeks later, each group was randomly divided into 4 subunits, namely: The peaceful group, the quota load group, the instantly exhausting group and the renewing group. Exhausting time was recorded. SOD activity, MDA content, GSH content and PLA2 and GOT activity of the cardiac muscle organisms from bodies executed at the corresponding. The time were all determined. All data was handled with single factor variance analysis and T examination by SPSS13.0 software. The significance reached is P<0.05.Results: 1. In peaceful conditions, SOD activity and GSH contents of group B, C, D showed little higher than those of group A, while as far as MDA content was concerned, the situation was opposite. The change of PLA2 activities wasn't obviously.2. At quotas loads condition, SOD activity and GSH content of group B, C, D were higher than those of group A. The PLA2 activity and the MDA content were in the opposite situation.3. After exhausting instantly, in the big mouse cardiac muscle, SOD activity of group B, C and D showed obviously higher than that of group A, but MDA, GSH content of each group nearly showed no difference. The PLA2 activity of group A showed obviously higher than that of group B, C and D.4. The renewing group after restoring for 12 hours, in cardiac muscle, SOD activity, MDA content, PLA2 activity in group D showed the lowest among the four groups, but GSH content in group D showed the highest among the four groups.5. Compared with other three groups of exhausting, group D showed significant difference in exhausting time, group A showed significant difference (PO.05) compared with group B and C, when compared with group C, group A showed larger significance.Conclusion: 1. Compound of Chinese traditional sturdy-positive-medicine prescriptions could coordinate the movement training, lengthen movement time, improve the mobility, postpone exhausting time site for the big mouse.2. Compound of Chinese traditional sturdy-positive-medicine prescriptions could reduce the MDA content, suppress lipin peroxidation and effectively remove free radicals in the cardiac muscle, raise the SOD activity and the GSH content in cardiac muscle of big mouse, sharpen the anti-oxidization ability of organism in different functional conditions.3. Compound of Chinese traditional sturdy-positive-medicine prescriptions and the training all can raise GOT active of cardie muscle in the big mouse, improve cardie muscle function, enhances the ability of cardie muscle to oxygen energy suplying under the different situation.4. Trainings could reduce the MDA content, suppress peroxidation of lipin, raise the SOD activity and the GSH content in the cardiac muscle of big mouse, enhance the anti-oxidized ability of organisms.5. In the state of movement, both the compound Chinese native medicine prescription and the movement training could prevent PLA2 activity fromincreasing, so as to reduce the damage for cardiac muscle, and further accelerate the damage restoration in cardiac muscle. If the two methods work together, the effect would be better. |
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