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The Research Progress Of New Diagnosis In NSCLC With MiRNA

Posted on:2018-07-24Degree:MasterType:Thesis
Country:ChinaCandidate:Y L HeFull Text:PDF
GTID:2334330518962076Subject:Internal Medicine
Abstract/Summary:PDF Full Text Request
Lung cancer is still a challenge in the medicalfield,the early symptoms is very hard to detect,so it's really diffcult for early diagnosis and therapy.MicroRNAs(miRNAs)consist of 22 nucleotides and are a class of endogenous ribo-regulators that modulate gene expressionevolutionary conserved RNA molecules that negatively regulate gene expression at the post-transcriptional level and could be maintain very stable.As is know,there is some special MicroRNA could be found in the cancer patients' blood.Newly study show expression of miRNA-was positively associated with lymph node metastasis,clinical diagnosis,poor prognosis and drug resistance.This article will summarise the function of niRNA about early diagnosis,prognosis and therpy.in the NSCLC.
Keywords/Search Tags:lung cancer, miRNA, miRNA-21, miRNA-145, miRNA-143
PDF Full Text Request
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