Lung cancer is still a challenge in the medicalfield,the early symptoms is very hard to detect,so it's really diffcult for early diagnosis and therapy.MicroRNAs(miRNAs)consist of 22 nucleotides and are a class of endogenous ribo-regulators that modulate gene expressionevolutionary conserved RNA molecules that negatively regulate gene expression at the post-transcriptional level and could be maintain very stable.As is know,there is some special MicroRNA could be found in the cancer patients' blood.Newly study show expression of miRNA-was positively associated with lymph node metastasis,clinical diagnosis,poor prognosis and drug resistance.This article will summarise the function of niRNA about early diagnosis,prognosis and therpy.in the NSCLC. |