Effect Of Jinqi Shenqi Pill On Renal Function In Aged Rats During Exercise

1objective:By investigating the influence of Jinkui shenqi wan and exercise on olderly rats'kidney function index.To discuss the effect that Jinkui shenqi wan enhance the olderlyrats kidney function.It can provide some scientice theory basis on older people'smovement training.2MethodFemale wiser rats selected80, were randomly divided into eight groups: controlgroup, medication group,20min exercise group,40min exercise group,60minexercise group,20min sports medicine group,30min sports medicine group,40minsports medicine group.And will select only10youth rats of six ZhouLing as a controlgroup.exercise group and sports medicine group rats increased by8weeks treadmilltraining load, while medication group and sports medicine group were fed “Jinkuishenqi wan”every day. Eight weeks later,we will take blood by picking eyeball andtake the kidney tissue for determine ureanitrogen?serum creatinine,uric acid?SOD?MDA?All data SPSS17.0statistical software used to conduct an independentsamples T-test significant difference for P <0.05.3Results:3.1the content of ureanitrogen in serum, medication group?40min exercise groupand40min sports medicine group were significantly less than control group (P<0.01),young group and20min exercise group were significantly lower than controlgroup (P <0.05),40min sports medicine group was significantly lower than20minsports medicine group and60min sports medicine group (P <0.05)3.2the content of creatinine in serum, medication group was significantly lowerthan control group (P <0.05), young group?20min exercise group?40min sportsmedicine group three's have significant difference compared with the control group (P<0.01).40min sports medicine group was significantly lower than control group (P<0.05),40min sports medicine group was significantly lower than20min sportsmedicine group and60min sports medicine group (P <0.01)?3.3he content of uric acid in serum?medication group?20min exercise group?20min sports medicine group and40min sports medicine group were significantlylower than control group (P<0.05),60min exercise group was significantly higherthan control group (P<0.05), young group was significantly lower than control group (P <0.01),20min exercise group and20min exercise group were significantly lowerthan60min exercise group (P <0.05),40min sports medicine group wassignificantly lower than60min sports medicine group (P<0.05),20min exercise groupand40min exercise group have no significant differences (P>0.05),20min sportsmedicine group and40min sports medicine group have no significant differences (P>0.05)3.4the activity of SOD in renal tissue,young group?40min sports medicine groupand60min sports medicine group were significantly higher than control group (P<0.01), group B and20min sports medicine group were significantly higher thancontrol group (P <0.05),60min sports medicine group was significantly higher than60min exercise group (P<0.05),40min sports medicine group was significantlyhigher than40min exercise group (P <0.05).3.5the content of MDA in renal tissue,young group, medication group,20minsports medicine group and40min sports medicine group were significantly lower thancontrol group (P<0.05),40min exercise group and60min exercise group weresignificantly lower than control group (P <0.05),60min exercise group wasignificantly higher than20min exercise group (P <0.05),60min exercise group wasignificantly higher than40min exercise group (P <0.01),20min sports medicine groupwas significantly lower than60min sports medicine group (P<0.05),40min sportsmedicine group was significantly lower than60min sports medicine group (P <0.01).4Conclusion:4.1Jinkui shenqi wan and moderate exercise can reduce rats of urea in serumcreatinine and uric acid,make old rats of glmerular filtration rate increase,it canprotect the function of kidney actively.4.2Incubi shenqi wan and moderate exercise can reduce the content of MDA inrats'kidney tissues and improve the activity of SOD in kidney tissue,restrain the lipidperoxidation,make free radicals are effectively cleared.4.3Jinkui shenqi with sports training can protect rats' kidney function and theeffect is more apparent than medication group and exercise group.