Analysis Of Correlative Factors And Tcm Syndromes Of Intestine Polpy

Purpose: The study aimed to observe the general characteristics of intestinal polyp patients were retrospectively analyzed,and through the comparison of patients with polyps and colon polyps group general biological characteristics,risk factors,this study was to evaluate colon polyps to intestinal polyps found by common clinical factors of risk,suggest that the early detection and prevention intervention.Through statistics and analysis of the distribution of TCM syndromes in patients with intestinal polyps whose main manifestation was diarrhea,the clinical characteristics of TCM and the relationship between them and other factors were found.Methods: A total of 838 patients who received electronic colonoscopy at the Splenic and Gastric Department of Geriatrics Center of the First Affiliated Hospital of Anhui University of Chinese Medicine on October 1,2018 and September 31,2020 were collected and divided into the polyp-free group(n < 288)and intestinal polyp group(n <550).Collect the information such us patient’s medical records,including age,sex,clinical manifestation,is there a nonalcoholic fatty liver disease,whether to have the gallbladder disease,blood lipid level,uric acid,whether helicobacter pylori infection and serum gastric-17 and so on.Data application was sent into SPSS 25.0 software for the single factor analysis,meaningful factors sent into many binary Logistic regression model to be analyzed.The medical records of patients with intestinal polyps with diarrhea as the main clinical manifestations were reviewed,including clinical manifestations,tongue coating,pulse and other symptoms of TCM syndrome differentiation.The distribution of TCM syndromes in patients with diarrhea intestinal polyps and their relationship with other factors were statistically analyzed.Results:1.In this study,there were 309 males and 241 females in the midgut polyp group,and 288 patients in the non-polyp group,including 128 males and 160 females.There were more males than females in the intestinal polyp group(male to female ratio was 1.28:1).In the non-polyp group,the youngest age ranged from 14 to 83 years old,with an average age of 52.76 years;in the intestinal polyp group,the youngest age ranged from 23 years old to 97 years old,with an average age of 58.69 years old.There were differences in age and sex distribution between the two groups(P < 0.05).2.The sigmoid colon is the most common site of polyps,followed by rectum,transverse colon,descending colon,ascending colon,ileocecal region,rectoethylene junction,and cecum.Most polyps were <0.5cm in size,followed by 0.5-0.9cm polyps,and > 2cm polyps were the most rare.The number of polyps was mainly multiple(304 cases),accounting for 55.3% of the total intestinal polyps.3.Adenomatous polyps were the main pathological distribution of polyps in the large intestine(66.5%),among which the most common polyps were tubular adenomas(246),followed by hyperplastic polyps(165).Juvenile polyps and serrated adenomas were less common.The incidence of adenomatous polyps was significantly correlated with age(P< 0.01),and the incidence of adenomatous polyps increased with the increase of age.4.There was statistically significant difference in triglyceride levels between the intestinal polyp group and the non-polyp group(P < 0.05).The triglyceride level of intestinal polyp group was higher than that of non-polyp group.There were no significant differences in total cholesterol and low density lipoprotein levels between the two groups(P BBB 0 0.05).The level of uric acid in male patients with intestinal polyps was higher than that in non-polyps group(P < 0.05),but there was no significant difference in the level of uric acid in female patients(P > 0.05).There was no significant difference in serum gastrin-17 level between the two groups(P BBB 0 0.05).The incidence of non-alcoholic fatty liver disease,helicobacter pylori infection,colonic diverticulum and gallbladder disease in intestinal polyp group were higher than those in non-polyp group(P < 0.05).There was no difference in the incidence of melanosis of the colon between the two groups(P BBB 0 0.05).Multivariate binary logistic analysis showed that gender,age and elevated triglyceride were independent risk factors for intestinal polyps(P < 0.05).5.The TCM syndromes of patients with diarrhea type intestinal polyps accounted for a large proportion of spleen and stomach qi deficiency syndrome(45.6%),followed by intestinal damp-heat syndrome(27.2%).There was a certain relationship between TCM syndrome type and polyp number and pathological type(P < 0.05).Single polyps were mainly found in the syndrome of liver qi taking advantage of spleen and the syndrome of spleen and stomach weakness,while multiple polyps were mainly found in the syndrome of intestinal damp-heat.Compared with the adenomatous polyps,non-adenomatous polyps were more common in the syndrome of Qi deficiency of spleen and stomach,dampness-heat of intestines,and cold-dampness-trapped spleen.Conclusion: 1.The gender of patients with colonic polyps is mainly male.Middle-aged and elderly patients are the most common.2.Colonic polyps tend to occur in the sigmoid colon and rectum.The cecum is the least.The size of polyps was mainly <0.5cm,and the number of polyps was mainly multiple.3.Adenomatous polyps and hyperplastic polyps were the most common pathological types of polyps in the large intestine,and the pathological types were correlated with age.4.The occurrence of intestinal polyps is related to age,sex and elevated triglyceride,and may be related to helicobacter pylori infection,gallbladder disease and non-alcoholic fatty liver disease.Elevated uric acid may be associated with intestinal polyps in men,but not in women.5.Diarhoea type colon polyp syndrome of traditional Chinese medicine is the most common deficiency of spleen qi syndrome,followed by intestinal dampness-heat syndrome.The syndromes of traditional Chinese medicine are related to the number and pathological types of polyps.Intestinal damp-heat syndrome is prone to multiple polyps,while the syndrome of Liver Qi multiplying the spleen and the syndrome of spleen and stomach weakness is prone to single polyps.Non-adenomatous polyps were more likely to occur in the syndrome of liver qi taking advantage of spleen,and adenomatous polyps were more likely to occur in the syndrome of deficiency of spleen qi and intestinal dampness-heat.