Study On Medication Rule Of Professor Lu Jianqi In Treating Stable Coronary Heart Disease

Objective: To study the medication rules of Professor Lu Jianqi,a famous Traditional Chinese medicine doctor from Guang Xi,in the treatment of Stable coronary artery disease(SCAD),and analyze the frequency of common drugs,the law of sexual taste and common drug combinations in the treatment of different syndrome types of Stable coronary artery disease.To summarize professor Lu Jianqi’s syndrome differentiation,medication and diagnosis and treatment rules in the treatment of stable coronary heart disease in order to pass on the valuable academic experience of professor Lu Jianqi,a famous traditional Chinese medicine doctor from Guang Xi,in a more scientific and objective way.Methods: Patients with stable coronary heart disease treated in Professor Lu Jianqi’s outpatient department of the First Affiliated Hospital of Guang Xi University of Chinese Medicine from January 2019 to December 2021 were included in the study.Medical records with clear diagnosis of Traditional Chinese medicine and western medicine,complete basic information,complete information of traditional Chinese medicine four diagnosis and clear prescription information were selected.After standardized processing of the included medical record data,a database was established,and the ancient and modern medical record cloud platform(V2.3.5)was used to carry out age distribution statistics,gender composition ratio statistics,syndrome type distribution statistics and syndrome element statistics of medical record data.Statistics of clinical symptoms and pulse pattern,medication frequency,four qi and five flavors of commonly used drugs,drug syndrome association statistics,drug association rules statistics and drug cluster analysis statistics were carried out for each syndrome type.Common drugs of different syndrome types,the law of sexual taste and meridian of drugs and common drug combinations of each syndrome type were counted.To summarize professor Lu Jianqi’s syndrome differentiation thinking,medication and diagnosis and treatment rules in the treatment of stable coronary heart disease,and to summarize,sort out and refine professor Lu Jianqi’s differentiation and treatment rules in the treatment of stable coronary heart disease.Results: A total of 221 patients’ medical records that met the standards were included in this study.After analysis on the ancient and Modern medical record cloud platform(V2.3.5),the results were as follows:1.The age of SCAD patients included in this study was mainly50-89 years old(76.92%),with 118 cases(53.39%)being male.The syndromes of patients mainly include phlegm turbidity,Yin deficiency,qi deficiency,Yang deficiency,cold evil and blood stasis.Some syndromes and miscellaneous syndromes appear and influence each other.2.Five syndrome types were mainly involved in this study,namely,phlegm and turbidness obstruction syndrome(27.60%)of qi and Yin deficiency syndrome(15.38%),Yin and cold stagnation syndrome(13.57%),blood stasis syndrome(26.24%),and heart and kidney Yang deficiency syndrome(17.19%).3.Statistical analysis of the common clinical symptoms of different syndrome types showed that the main clinical manifestations of phlegm turbidity bi obstruction syndrome were: chest tightness,shortness of breath,heavy limbs and palpitation,etc.Common tongue and pulse symptoms were fat tongue,teeth marks,white moss,and smooth pulse string.The main clinical manifestations of qi and Yin deficiency syndrome are palpitation,dizziness,fatigue and fatigue,chest pain,etc.Common pulse symptoms are red tongue,thin white moss,and thin pulse.The main clinical manifestations of Yin cold stagnation syndrome are chest distension,chest pain,hand and foot temperature,palpitations,etc.Common pulse symptoms are pale red tongue,thin white moss,and heavy pulse.The main clinical manifestations of blood stasis syndrome are: chest pain,palpitation,needle-like pain,pain with fixed location,etc.Common pulse symptoms are dark red tongue,thin white moss,and heavy and astringent pulse.The main clinical manifestations of heart-kidney Yang deficiency syndrome are palpitation,fear of chills,chest pain,loose stools,etc.Common tongue and pulse symptoms are light red tongue,white moss,and heavy pulse.4.Statistical analysis of the four qi,five flavor and meridian of stable coronary heart disease drugs showed that the four qi of the drugs were mainly warm,flat and cold,the five flavors were mainly sweet,spicy and bitter,and the main meridian of heart,lung,spleen and kidney.5.According to the statistical analysis of the commonly used drugs of different syndrome types,the treatment method of phlegm-turbidness obstructing SCAD was "dissipating phlegm and clearing phlegm".A total of 110 drugs were used,including fructus trichosanthes,allium allium,pinellia blanchia,blanchia almond,Poria coxsackie,etc.The treatment of SCAD with deficiency of qi and Yin was "nourishing Qi and Yin".A total of 64 drugs were used,including processed glycyrrhiza glycyrrhiza,ginseng,Chinese jujube,Radix Ophiopogonis,Atractylodes atractylodes,etc.The treatment of Yin and Cold retarding SCAD was "warming Yang and disperses cold",and 55 kinds of drugs were used,including aconite,coix seed,Tuckahoe,chuanxiong,etc.The treatment of blood stasis type SCAD is "promoting blood circulation and removing blood stasis".A total of 52 drugs were used,including safflower,peach kernel,rehmannia glutinosa,ligusticum chuanxiong,etc.The treatment of SCAD with heart,kidney and Yang deficiency was "warming and tonifying heart and kidney".A total of 85 drugs were used,including supplementary tablets,prepared glycyrrhiza glycyrrhiza,cooked rehmannia glutinis,cornus officinalis and Chinese yam.6.The drug combination of professor Lu Jianqi’s therapeutic drugs was obtained through data mining of the auxiliary platform.Professor lu by the method of scallions white-snakegourd fruit-pinellia poria cocos-bitter almond and other drug combination treatment of phlegm turbidity bizu,astragalus membranaceus-jujube-dwarf lilyturf,ginseng-main licorice-atractylodes drug combination treatment of qi and Yin deficiency syndrome,semen coicis-lateral root of aconite poria cocos-scallions white-the drug combination treatment such as fructus Yin cold stagnate,safflower,peach kernel,radix rehmanniae,radix bupleuri drug combination treatment such as blood stasis resistance,Drug combination of Epimedium-Fu Shen-attached tablet-prepared glycyrrhiza to treat the syndrome of deficiency of heart and kidney Yang.Conclusion:1.Among the 221 cases of SCAD treated by Professor Lu Jianqi,phlegm and turbidness syndrome was the most common,followed by blood stasis syndrome,heart and kidney Yang deficiency syndrome,qi and Yin deficiency syndrome,and Yin and cold stagnation syndrome.2.Professor Lu Jianqi believes that the occurrence of SCAD is closely related to the obstruction of chest Yang.The basic pathogenesis of SCAD is the deficiency of qi,blood and Yin in the heart,and the deficiency of Yin and Yang in the heart,and the deficiency of phlegm,blood stasis and cold evil.3.Professor Lu Jianqi used xinwen products for the treatment of SCAD,including the four channels of main heart,lung,spleen and kidney;Allium macrostemon,Fructus trichosanthes,Aconite,Ligusticum chuanxiong,Rhizome rhizome and Poria cocos are commonly used.4.In the treatment of SCAD,Professor Lu Jianqi closely adhered to his academic thought of "treating heart without being too warm,and treating bi without being too general",scrupulously adhered to the treatment of "warming Yang through BI",and also paid attention to the influence of "region" and "constitution" factors on syndrome differentiation and treatment.