Based On Data Mining,the Syndrome Of TCM And The Medication Rule Of Senile Osteoporosis Combined With Anxiety And Depression Were Explored

Objective:With the help of the TCM inheritance computing platform(V3.0),the TCM syndrome type and prescription medication rules of elderly osteoporosis combined with anxiety and depression were discussed,providing reference for clinical treatment.Methods:The hospital electronic medical records system for the medical records of elderly patients with anxiety and depression hospitalized in the Department of Geriatric Medicine of Shandong University of Traditional Chinese Medicine during 2017.01.01-2021.12.31,the "data analysis" system of TCM inheritance computing platform(V3.0),the module functions of "statistical analysis,prescription analysis" were used for data mining of TCM prescriptions,summarized the TCM certificates of elderly patients with anxiety and depression in recent years,and the rules of drug use were analyzed.Results:After screening,317 prescriptions were sorted out,including 72 sputum stasis obstruction,70 liver and kidney deficiency,66 qi deficiency and blood stasis deficiency,49 qi and Yin deficiency,30 liver stagnation and qi stagnation,and 30 phlegm and heat stagnation.Statistical analysis shows that the following:(1)The treatment of phlegm stasis of 72 first prescription efficacy to fill deficiency,promoting blood stasis,common compatibility drug combination is Pinelliae Rhizoma and Atractylodis Macrocephalae Rhizoma,Pinelliae Rhizoma and Poria,Atractylodis Macrocephalae Rhizoma and Poria,Pinelliae Rhizoma and Chuanxiong Rhizoma,Persicae Semen and Carthami Flos,Pinelliae Rhizoma and Citri Reticulatae Pericarpium,Pinelliae Rhizoma and Atractylodis Macrocephalae Rhizoma and Poria,analysis association rules,visible Gastrodiae Rhizoma and Pinelliae Rhizoma is fixed in use.The core medication is pinellia white surgery Gastrodia elata soup and peach red four things soup added and reduced,extract the core combination,get 3 new square:1)Pinelliae Rhizoma,Chuanxiong Rhizoma,Atractylodis Macrocephalae Rhizoma,Persicae Semen,Carthami Flos;2)Pinelliae Rhizoma,Atractylodis Macrocephalae Rhizoma,Astragali Radix,Poria,Coicis Semen;3)Pinelliae Rhizoma,Salviae Miltiorrhizae Radix Et Rhizoma,Atractylodis Macrocephalae Rhizoma,Gastrodiae Rhizoma,Glycyrrhizae Radix Et Rhizoma.(2)The treatment of liver and kidney deficiency of 70 prescription efficacy to fill deficiency,promoting blood stasis,common compatibility drug combination is Achyranthis Bidentatae Radix and Eucommiae Cortex,Achyranthis Bidentatae Radix and Angelicae Sinensis Radix,Taxilli Herba and Eucommiae Cortex,Achyranthis Bidentatae Radix and Paeoniae Radix Alba,Poria and Angelicae Sinensis Radix,Achyranthis Bidentatae Radix and Taxilli Herba,Achyranthis Bidentatae Radix and Poria,Angelicae Sinensis Radix and Chuanxiong Rhizoma,analysis association rules,visible Achyranthis Bidentatae Radix and Taxilli Herba and Eucommiae Cortex is fixed in use.The core medication is the single live parasitic soup,extract the core combination,get 3 new square: 1)Poria,Achyranthis Bidentatae Radix,Rehmanniae Radix Praeparata,Atractylodis Macrocephalae Rhizoma,Corni Fructus;2)Angelicae Pubescentis Radix,Chuanxiong Rhizoma,Angelicae Sinensis Radix,Taxilli Herba,Poria;3)Glycyrrhizae Radix Et Rhizoma,Achyranthis Bidentatae Radix,Paeoniae Radix Alba,Eucommiae Cortex,Rehmanniae Radix.(3)The efficacy of 66 prescriptions for the treatment of qi deficiency and blood stasis is mainly to replenish deficiency,promote blood circulation and remove blood stasis,and the commonly used compatibility drugs are Astragali Radix and Chuanxiong Rhizoma,Astragali Radix and Angelicae Sinensis Radix,Astragali Radix and Persicae Semen,Astragali Radix and Paeoniae Radix Rubra,Chuanxiong Rhizoma and Angelicae Sinensis Radix,Angelicae Sinensis Radix and Paeoniae Radix Rubra,Astragali Radix and Angelicae Sinensis Radix and Paeoniae Radix Rubra,Astragali Radix and Glycyrrhizae Radix Et Rhizoma,analysis association rules,visible Chuanxiong Rhizoma and Persicae Semen and Astragali Radix is fixed in use.The core medication is tonic Yang also five soup plus and minus,extract the core combination,get 4 new square:1)Chuanxiong Rhizoma,Astragali Radix,Angelicae Sinensis Radix,Atractylodis Macrocephalae Rhizoma,Poria,Amomi Fructus;2)Astragali Radix,Carthami Flos,Persicae Semen,Angelicae Sinensis Radix,Chuanxiong Rhizoma,Paeoniae Radix Rubra;3)Poria,Glycyrrhizae Radix Et Rhizoma,Persicae Semen,Chuanxiong Rhizoma,Angelicae Sinensis Radix,Astragali Radix;4)Astragali Radix,Paeoniae Radix Rubra,Angelicae Sinensis Radix,Atractylodis Macrocephalae Rhizoma,Chuanxiong Rhizoma,Poria.(4)The efficacy of 49 prescriptions for the treatment of qi and Yin deficiency is mainly tonifying deficiency and clearing heat,and the combination of commonly used compatibility drugs are Ophiopogonis Radix and Schisandrae Chinensis Fructus,Ophiopogonis Radix and Astragali Radix,Astragali Radix and Atractylodis Macrocephalae Rhizoma,Ophiopogonis Radix and Atractylodis Macrocephalae Rhizoma,Ophiopogonis Radix and Poria,Atractylodis Macrocephalae Rhizoma and Poria,analysis association rules,visible Schisandrae Chinensis Fructusis and Ophiopogonis Radix fixed in use.The core medication is raw pulse loose astragalus cinnamon wu soup,extract the core combination,get 4 new square:1)Poria,Ophiopogonis Radix,Astragali Radix,Pseudostellariae Radix,Atractylodis Macrocephalae Rhizoma,Achyranthis Bidentatae Radix;2)Ophiopogonis Radix,Schisandrae Chinensis Fructus,Astragali Radix,Atractylodis Macrocephalae Rhizoma,Paeoniae Radix Alba,Poria;3)Atractylodis Macrocephalae Rhizoma,Ophiopogonis Radix,Poria,Hordei Fructus Germinatus,Divine Tune,Schisandrae Chinensis Fructus;4)Angelicae Sinensis Radix,Astragali Radix,Ophiopogonis Radix,Glycyrrhizae Radix Et Rhizoma Praeparata Cum Melle,Cinnamomi Ramulus,Salviae Miltiorrhizae Radix Et Rhizoma.(5)The efficacy of 30 prescriptions for the treatment of Liver stagnation syndrome is mainly to promote blood circulation and remove blood stasis,replenish deficiency,and the combinations of common compatibility drugs are Carthami Flos and Persicae Semen,Chuanxiong Rhizoma and Persicae Semen,Chuanxiong Rhizoma and Carthami Flos,Chuanxiong Rhizoma and Angelicae Sinensis Radix,Chuanxiong Rhizoma and Glycyrrhizae Radix Et Rhizoma.Analyzing the association rules,it can be seen that Glycyrrhizae Radix Et Rhizoma and Carthami Flos and Persicae Semen,Chuanxiong Rhizoma and Glycyrrhizae Radix Et Rhizoma and Carthami Flos and Persicae Semen are relatively fixed in use,and the core medication is Chai hu shu liver loose peach four mixture,extract the core combination,get 4 new square:1)Atractylodis Macrocephalae Rhizoma,Bupleuri Radix,Glycyrrhizae Radix Et Rhizoma,Carthami Flos,Coptidis Rhizoma,Persicae Semen;2)Paeoniae Radix Alba,Bupleuri Radix,Glycyrrhizae Radix Et Rhizoma,Pinelliae Rhizoma,Salviae Miltiorrhizae Radix Et Rhizoma,Aurantii Fructus;3)Chuanxiong Rhizoma,Paeoniae Radix Alba,Carthami Flos,Persicae Semen,Bupleuri Radix,Poria;4)Chuanxiong Rhizoma,Persicae Semen,Angelicae Sinensis Radix,Carthami Flos,Paeoniae Radix Alba,Glycyrrhizae Radix Et Rhizoma.(6)The efficacy of 30 prescriptions for the treatment of phlegm and heat gas is mainly clearing heat,resolving phlegm,relieving cough and relieving asthma,and the combinations of common compatibility drugs are Coptidis Rhizoma and Glycyrrhizae Radix Et Rhizoma,Coptidis Rhizoma and Citri Reticulatae Pericarpium,Coptidis Rhizoma and Pinelliae Rhizoma,Citri Reticulatae Pericarpium and Pinelliae Rhizoma,Citri Reticulatae Pericarpium and Poria,Citri Reticulatae Pericarpium and Glycyrrhizae Radix Et Rhizoma,Coptidis Rhizoma and Poria.Analyzing the association rules,it can be seen that Glycyrrhizae Radix Et Rhizoma and Pinelliae Rhizoma and Coptidis Rhizoma are relatively fixed in use,and the core drug is added and decreased by coptis warm bile soup,extract the core combination,get 3 new square:1)Coptidis Rhizoma,Glycyrrhizae Radix Et Rhizoma,Citri Reticulatae Pericarpium,Platycodonis Radix,Gardeniae Fructus;2)Coptidis Rhizoma,Pinelliae Rhizoma,Bambusae Caulis In Taenias,Glycyrrhizae Radix Et Rhizoma,Citri Reticulatae Pericarpium;3)Citri Reticulatae Pericarpium,Poria,Glycyrrhizae Radix Et Rhizoma,Atractylodis Macrocephalae Rhizoma,Pinelliae Rhizoma.Conclusion:According to the data results,it is concluded that the TCM syndrome types of senile osteoporosis combined with anxiety and depression mainly include sputum stasis,liver stagnation,phlegm and hot gas knot,and liver and kidney deficiency,qi deficiency and blood stasis,and qi and Yin deficiency.The following rules are summarized: the treatment of the disease in the hospital is mostly based on the "concept of shape and mind",paying attention to the harmony of shape and mind,the overall treatment is mainly healthy,and is good at using the drug taste to regulate the qi,blood,Yin and Yang,to achieve the purpose of shape and mind and treating both the symptoms and root causes.