The 40 Cases Of Curative Effect Observation About Treating CRF With The Method Of Releasing Excessive Turbid And Invigorate The Spleen,Tonifying The Kidney

Objective:(1)To summary TCM and Modern Medicine in recognizing chronic renal failure and research progression. (2)To observe the release excessive turbid and invigorate the spleen , tonifying the kidney on treatment of Chronic Renal Failure (CRF) . Methods:(1)The literature research: To summary and evaluate the pathogenesy and prevention and cure SQ of CRF thought referring to packs of Chinese and foreign literature from ancient times and modern times.(2) Clinical research: To observe 40 cases of CRF patient thought the method of prospective self AP comparison. To observe the release excessive turbid and invigorate the spleen , tonifying the kidney on treatment of Chronic Renal Failure (CRF) in the foundation of essential treatment, adjusting the Chinese medicinal materials from the change of the syndrome.. To observe the present symptoms and syndrome (asthenia of lumbar and knees, fatigued and weak, drying of the mesopharynx , burning sensation of five centers, puffiness, chilly and calefactionphile, dizziness and dizzy, hectic fever and night sweat, algor of limbs, multitude of nycturia, restless and tantrum, fullness in chest and hypochondrium, bitter taste of mouth, glooming of labia oris, ecchymosis of body, obfuscation of eye ring, squamous and dry skin) and the experimentation index of Scr and Bun in 4 months. Result: (1)The literature research:CRF is the eventually gr of variouskindsof kidney diseases and hasn' t a specified name in TCM. But it' smentioned in the record of such as "Guange" , "Nidu" , "Shuizhong", "Xulao", " Longbi" .The decline of kidney and spleen makes the triple warmer bunged with turbid pathogen" is the basic pathogenesis of CRF. Recent years Traditional Chinese Medicine has made a big progress in treating CRF. Its major treatment is including promoting blood flow and removing blood stasis, invigorate the spleen and tonifying kidney, dispelling dampness and turbid. There are other treatments such as empirical formula and single Chinese medicinal materials. The major mechanisms in treating CRF with Chinese medicinal materials is : l.To relieve the hypermetabolism condition of the remained nephron and improve the hemorrheology condition. As a result to restraint the glomerular sclerosis and interstitial fibrosis;2.To improve the metabolism of fatty substance;3. To improve the sys. Nutritional status and elevate the immunity;4. To decrease the Urine protein. Modern Medicine in treating CRF is peroral intestinal tract adsorbate. And especially drug such as prostaglandin, sodium ferulate, oxoacid preparation and symptomatic treatment like controlling hypertension. (2) Clinical research: To compare the 40 cases of CRF from pretherapy to post-treatment. The result is 40% excellence, 52. 5% utility and the total effective rate is 92. 5%. The complaint integrate in pretherapy is 26.58 + 10.83 while in post-treatment is 17.75 ± 12.37(P<0. OD.SCr decrease 70.07 ± 23.23umol/L comparing to pretherapy(P<0.05). BUN decrease 3.05 ± 0.90 mmol/L comparing to pretherapy(P<0. 05).Conclusion: CRF is the eventually gr of various kinds of kidney diseases and " the decline of kidney and spleen makes the triple warmer bunged with turbid pathogen" is the basic pathogenesis of CRF. TCM is ascenden in treating CRF with indialysis regimen. The release excessive turbid and invigorate the spleen > tonifying the kidney on treatment of Chronic Renal Failure (CRF) is consistent with TCM determination of treatment based in pathogenesis obtained through differentiation of symptoms and signs basic theory. And it has favourable research perspective.2. The release excessive turbid and invigorate the spleen > tonifying the kidney on treatment of Chronic Renal Failure (CRF) has invariably therapeutic effect. And it can depress urea nitrogen and serum creatinine. And it can improve the patients' clinical symptom. It can also delay the proceeding ofCRF.