Clinical Study On Advanced Non-small Cell Lung Cancer Treated By Zheng Ji Capsule Combined With Chemotherapy

Objective:According to the pathogenic peculiarity of stasis,toxicity and phlegm obstruction,"Zheng Ji capsule" based on the therapeutic principle of Huayu and expectoranting,detoxicating and resolving a mass was Studied out for non-small cell lung cancer(NSCLC),combined with chemotherapy to observe the effects of the treatment, and to probe into its mechanism of action.MethodS:Adopting a random method,46 cases of non-small cell lung cancer patients were divided into treatment and control groups avemgely,two sets were given TP(PTX+DDP) chemotherapy,and the observation set even took Zheng Ji capsules.Carrying on prospective study,Objective effects and the changes of subjective symptoms were studied during two periods of treatment.Results: After two periods of treatment,the subjective symptoms,KPS,body weights,quality of life,side effects,immune parameters(NKC),the tumor mark(CEA) were all significantly improved in the treated set,better than in the control one.But there was no difference between two groups on the size of focus,the toxicity occurent rate and toxic degree were slighter in the treated group than in the control one.Conclusion:"Zheng Ji capsule" combined with chemotherapy(TP regimen)have better curative effect on treating NSCLC.