Effect Of Safflower Yellow Pigment On Blood Glucose Level In Elderly Patients With Diabetes Mellitus Complicated With Cerebral Infarction

Objective:Objective to study the effect of safflower yellow pigment on hemorheology,glucose metabolism and plasma C-peptide levels in elderly patients with diabetes mellitus complicated with cerebral infarction.METHODS:Patient selection:Simple senile patients with cerebral infarction in 60 cases of elderly patients with diabetes complicated with cerebral infarction in 60 cases,60 cases of healthy young subjects,venous blood of three groups of patients were fasting and 75g after oral glucose,and blood rheology,blood glucose,C peptide levels in elderly diabetic patients with cerebral infarction group.On the basis of conventional treatment given safflower yellow pigment lyophilized powder injection 100mg was injected into normal saline 250ml intravenously,once a every day,14 days for 1 course of treatment.First days and fourteenth days after admission,The venous blood was collected from fasting venous blood and oral glucose 75g respectively,Testing the blood rheology,fasting blood glucose,postprandial blood glucose,C peptide level.RESULTS:1.Senile cerebral infarction patients blood viscosity,red blood cell reduction index,plasma viscosity,erythrocyte aggregation index,hematocrit was significantly higher than that of young people(P<0.05),fasting blood glucose and oral glucose 2h,3h blood sugar compared to healthy young people increased significantly(P<0.05),no significant differences in fasting C peptide and health the young man,and after oral glucose 1,2,3hC peptide levels in healthy young people increased significantly(P<0.05),2?Elderly patients with diabetes mellitus complicated with cerebral infarction of safflor yellow after treatment,whole blood viscosity,red blood cell reduction index,erythrocyte aggregation index decreased significantly(P<0.01),plasma viscosity,RBC hematocrit decreased significantly(P<0.05);fasting blood glucose,oral glucose 1,2,3 hours after blood glucose was significantly lower than that before treatment(P<0.05 1,2 hours);the serum C peptide levels increased significantly after oral glucose(P<0.05),no change in 3 hours C peptide levels after oral glucose(P>0.05).Conclusion:Safflower yellow pigment can improve blood rheology,glucose metabolism and C peptide levels in elderly patients with cerebral infarction complicated with diabetes mellitus,and may play a certain role in the prevention and treatment of diabetes and its complications.