Clinic Study Of Treating Luteinized Unruptured Follicle Syndrome Of Endometriosis With Tonifying The Kidney And Promoting Blood Circulation

Luteinized Unruptured Follicle Syndrome (LUFS) is a difficult and complicated gynecopathy, which is mutually related to infertility. The incidence of this disease is 9-55% in common, 6%~83% in infertility , 50%~71% in pelvic inflammation, and 33%~83% in endometriosis(EMS). Since the prevalence is high in EMS-LUFS and the curative effect is not so good, the study on the mechanism of pathogenesis and the therapy about this disease is one of important research topic, which has aroused great general concerns.Tonifying the kidney and promoting blood circulation is an effective method to treat the EMS-LUFS in clinic. This study observed the clinic effect and researched the curative mechanism in random and contrast principles.The mechanism of EMS-LUFS is very complex. The majority scholars held the pathogenesis was a result of many levels. The modern Chinese medicine considered kidney deficiency and blood stasis was basic pathogenesis of EMS-LUFS. They discovered the whole bodies or pelvis were in the state of blood stasis. Since the disease lingering made deficiency of kidney and blood stasis. The modern medicine thought that "kidney deficiency" relates to the endocrinopathy of hypothalamus-pituitary-ovarian-axis (HPOA). In the study on the essence of blood stasis, the researchers discovered the patients was abnormal, changes had taken place in immunocyte and cytokine. The western medicine held that LUFS connect with endocrine dyscrasia and disorder of immune system, such as abnormal number and function of immunocyte, autoimmune antibodies emerging, complements depositing. All these caused ovarian and uterine perfusion decreased, and effected the follicular development. Thus LUFS happen and resulted in infertility. The results of recent studies throughout the world indicated that nerve-endocrine-immune system is important in mediating reproductive function. Many cytokines were related to hormone, at the same time Chinese medicine thought blood stasis could lead to kidney deficiency and the reverse was also true. The pathogenesis of EMS-LUFS was the dislocation of nerve-endocrine-immune system, and it was kidney deficiency and blood...