Objective: Based on the chronic renal failure (CRF) theory of consolidation and clinicalcase collection, Clinical observation of continuous Shengqing Jiangzhuo Decoction in thetreatment of CRF decompensated spleen qi deficiency type wet and muddy clinical curativeeffect, In order to further study the mechanism of action, seek effective, safe and reliablemethods to lay the foundation.Methods: Methods49patients with CRF decompensated spleen qi deficiency syndromediagnostic criteria were wet and muddy, Using a random number table for grouping, Thetreatment group (taking Qilian Shengqing Jiangzhuo Decoction) in25cases, Haikun Shenxigroup (taking Haikun Shenxi Capsule) in24cases, The two groups were in support oftreatment based on the oral drugs, With the uninterrupted drug for60days for a course of1,Observation1course. To observe the clinical symptoms after treatment of integral, Laboratoryindicators of change, The end of treatment results.Result:1.The treatment group of clinical symptoms in patients with total effective rate84%, Haikun Shenxi group66.67%, Two group P <0.05had significant difference, The effect ofthe treatment group is superior to control group.2.Two groups of symptom scores before treatment, there were no significant difference (P>0.05), after treatment were reduced, and the treatment group was better than that ofhaikunshenxi group, there was significant difference (P<0.05).3.Before the treatment group treated with Haikun Shenxi group Scr, BUN, Ccr statisticalanalysis, there were no significant difference (P>0.05), comparable; after treatment comparedwith those before treatment had a significant difference (P<0.05), and the treatment group, BUN,Scr were decreased, CCr was increased, treatment group is better than the Haikun Shenxi group,there was significant difference (P<0.05).4.In two groups of patients before blood RBC, Hb, statistical analysis, P>0.05, there wereno significant difference, comparable; the treatment group, blood RBC, Hb increasedsignificantly, treatment group was better than that of haikunshenxi group, there was significantdifference (P<0.05), compared with before treatment had a significant difference (P<0.05).5.The two groups before treatment and24hours urine protein, urine red blood cell counts, P>0.05, there was no significant difference between the two groups after treatment;24hour urineprotein, urine red blood cell counts, P <0.05, there was significant difference; the treatmentgroup before and after treatment in24hour urine protein and urine routine red blood cell count, P<0.05, there was significant difference; Haikun Shenxi group before and after treatment in 24hour urine protein quantitative comparison, P <0.05, there was significant difference of urinered blood cell counts, comparison, there was no difference between P>0.05of.Conclusion:1.In" rise clear and descending turbid" basic theory of traditional Chinesemedicine under the guidance of, to the tune of " Qi, hsxz" as a principle of treatment, use ofQilian Shengqing Jiangzhuo decoction, for a period of two months of treatment (treatmentgroup), and haikunshenxi group, clinical symptoms, have a positive effect.2.Through clinical observation, Qilian Shengqing Jiangzhuo Decoction in improving renalfunction, improve the level of patients with Hb, RBC, reduce quantitate of24hour urine proteinand urine red blood cell count level significant effect.3.Treatment of the implementation process, in two groups of patients have obviousdiscomfort symptoms, laboratory examination no abnormalities, inferred from the selectedRecipe on the safety index effect. |