The Effect Of Lycopene On The Exhausting Exercising Ability Of Training Rats

1 Research objectiveThe study researched the effect of lycopene and exercise on exhausting swimming time and the effect of lycopene and exercise on free radicals metabolim in serum,liver,heart and quadriceps of rats, to discuss the function of lycopene to increase exercise ability and its anti-fatigue ability, to instruct training and enhance the level of training ,furthermore to provide theory for sports nutrition .2 Research methodsSixty-four healthy male Kunming rats were selected and randomly divided into rest control group (sample scale-8) ; dosed rest group ( low,middle,high groups,sample scale-8 for each dose) ; training control group (sample scale-8); dosed training group (low,middle,high groups,sample scale-8 for each dose). training control group, dosed training group had swam for 6 weeks; rats in group rest control, and dosed rest took lycopene every day. After six weeks, each group swam till exhaustion then record swimming time and took blood from rats'eyepit, take out the heart,liver,quadriceps, to assay activities of SOD and GSH-PX, MDA content. The data are analyzed by SPSS11.5 , with the methods of univariate analyse ,the diversity is 0.05.3 Research results3.1 exhausting time: compared with rest control group, dosed training group, training control group, and dosed rest group(middle dose, high dose) had remarkably delayed the exhausting time(P<0.05),compared with rest control group, and dosed rest group(low dose ,middle dose), training control group had remarkably delayed the exhausting time(P<0.01),compared with training control group, dosed training group(middle dose, high dose) had remarkably delayed the exhausting time(P<0.01).3.2 MDA content in tissues: compared with rest control group, dosed rest group, training control group, dosed training group, MDA content had significantly decreased(P<0.01), compared with training control group, dosed training group, MDA content had significantly decreased (P<0.05)in heart, liver, quadriceps, and serum; there were significant interactions of lycopene and exercise training on MDA content in heart, and quadriceps of rats(P<0.05 ),while the interactions on MDA content in liver was not evidently(Pï¹¥0.05).3.3 SOD activity in tissues: compared with rest control group, SOD activity in dosed rest group, training control group, and dosed training group had significantly increased(P<0.01), compared with training control group, SOD activity in dosed training group had significantly increased(P<0.05)in, heart, liver, and serum; compared with rest control group, SOD activity in dosed rest group(high dose, middle dose), and training control group had significantly increased(P<0.01), compared with rest control group, and training control group, SOD activity in dosed training group had significantly increased (P<0.01)in quadriceps; there were distinct interactions of lycopene and exercise training on SOD activity in heart ,and quadriceps of tats(P<0.05 ). while the interactions on SOD activity in liver and serum was not evidently(Pï¹¥0.05).3.4 GSH-Px activity in tissues: compared with rest control group, dosed rest group, training control group, dosed training group GSH-Px activity had significantly increased(P<0.01)in heart , liver , quadriceps and serum ;compared with training control group, GSH-Px activity in dosed training group(middle dose, high dose) had significantly increased(P<0.01)in heart; compared with training control group, GSH-Px activity in dosed training group had significantly increased(P<0.01)in liver, quadriceps and serum .there were significant interactions of lycopene (low dose ,middle dose) and exercise training on GSH-Px activity in heart of rat(sP<0.01), there were significant interactions of lycopene (middle dose, high dose) and exercise training on GSH-Px activity in liver of rats(P<0.05 ), and the significant interactions of lycopene (high dose) and exercise training on GSH-Px activity are in quadriceps , and the significant interactions of lycopene (high dose) and exercise training in serum of rats(P<0.05).4 Conclusions4.1 Lycopene can cooperate with exercise training to postpone exhausting swimming time significantly, and increase abilities of exercise and resisting fatigue.4.2 Lycopene can cooperate with exercise training to increase activities of SOD and GSH-PX, and to decrease MDA content in serum, liver ,heart ,and quadriceps of rats , this cooperation control lipid peroxidation so as to enhance antioxidation abilities in different tissues.4.3 Go with the dose of lycopene increased, after once exhaust swimming, the activities SOD and GSH-PX in serum, liver ,heart ,and quadriceps of rats is increasing,and the MDA content is degressive. In one range(0-40mg/kg) , go with the dose of lycopene increased can enhanced antioxidation abilities in different tissues.